DestroyTwitter is a versatile twitter client. It packs in a ton of features while leaving an unbelievably small footprint. How does memory usage as low as 25mb sound? What about an installer under 1mb?
Filter the Noise
Tired of reading where your friends are? Filter Foursquare/Gowalla and you’re good to go. Someone on a tweeting spree at an event? Filter them or the event’s hashtag.
Font too small? Try medium or large. Don’t like icons? Get rid of them. Hate the notification sound? Choose from the five others. Need to read 200 tweets every 30 seconds? Done.